A multivariable Cox regression model adjusted for age, sex, hypertension, total cholesterol, HDL, and current smoking showed that the highest quartile of TGF-β2 remained associated with a lower risk for future CV events with a HR of 0.41 (95% CI 0.2–0.8, P = 0.02; Supplementary material online, Table S7) compared to the lowest quartile. This evidence concerns the gene TGFB2 and hypertensive disorder.