To test whether these findings also held true in human sarcomas, we used our isogenic 143B human sarcoma cell line with or without CRISPR ATRX knockout and assessed IFNB1 expression levels after treatment with oHSV-60, a 60-bp DNA sequence known to potently stimulate the CGAS/STING pathway. The gene discussed is IFNB1; the disease is sarcoma.