Univariate cox regression analysis showed that KLF11 (HR = 2.433, 95% CI = 1.407–4.208, p = 0.001), grading (HR = 1.940, 95% CI = 1.106–3.403, p = 0.021), tumor size (HR = 1.991, 95% CI = 1.301–3.047, p = 0.002) and lymph node status (HR = 1.832, 95% CI = 1.187–2.829, p = 0.006) were significantly associated with DFS across the BC cohort (Table 2). The gene discussed is KLF11; the disease is breast cancer.