Isolated cases of eosinophilic reactions have been reported during treatment with GLP-1 RAs, including peripheral eosinophilia, eosinophil-rich bullous pemphigus, acute interstitial nephritis, eosinophilic panniculitis, and eosinophilic hepatitis, among others [10–28]. The gene discussed is GLP1R; the disease is Increased total eosinophil count.