PML and infection: In contrast, we observed that during infection with particles from pHBV1.1 Δscm1/2-transfected cells, the cytoplasmic HBV core fraction was enhanced to 80%, while only 20% was found at the border of the nuclear DAPI staining; nothing could be detected in either the nuclear or the PML-NB fraction (Fig. 6B, panels p to r).