The expression of p-Akt and the apoptosis-related proteins Bcl-2 (anti-apoptotic protein), Bcl-xl (anti-apoptotic protein), and Bax (pro-apoptotic protein) are downregulated in IL-11 knockdown cells, revealing that IL-11 activates the PI3K/Akt signaling pathway in the treatment of radiotherapy-resistant cervical cancer [32, 34]. The gene discussed is IL11; the disease is cervical carcinoma.