Exploratory multivariable logistic regression models showed that independent risk factors for COVID-19 related mortality were higher age, being of Latin American origin, having a higher number of concomitantly diagnosed comorbidities, having a current CD4+ cell count below 500 cells/μl with an even higher risk when the CD4+ cell count was below 200 cells/μl (Table 4). This evidence concerns the gene CD4 and COVID-19.