Consequently, airway epithelium in patients with T2 asthma overproduces a broad pallet of pro-inflammatory cytokines and mediators including alarmins (IL-25, IL-33, TSLP), as well as IL-6, IL-8, IL-1α/β, RANTES, or TNF in response to environmental triggers. The gene discussed is TSLP; the disease is asthma.