Many studies have revealed that PRDX1-regulated ROS-dependent signaling pathways play a key role in the development of various cancers, including breast cancer [35, 36], esophageal cancer [37, 38], lung cancer [39, 40], prostate cancer [41, 42], and pancreatic cancer [43, 44]. The gene discussed is PRDX1; the disease is esophageal cancer.