Our database analyses indicated that the transcript levels of RARα and RARγ in pancreatic cancer (C) were significantly higher than those in normal pancreatic tissue (N) (RARα, mean TPM 41.1 vs. 5.6, p < 0.0001; RARγ, mean TPM 36.6 vs. 4.2, p < 0.0001) and that the transcript level of RARβ was low in both pancreatic cancer (C) and normal pancreatic tissue (N) (mean TPM 8.5 vs. 0.7, p < 0.0001) (Fig. 1a). Here, RARA is linked to familial pancreatic carcinoma.