Negative CTSK expression was observed in two cases of ACC (40%), two cases of low-grade MEC (28.6%), two cases of high-grade MEC (15.4%), one case of AdCC (8.3%), and one case of CXPA (12.5%, Fig. 2, collected Figs. 3, 4). The gene discussed is CTSK; the disease is adrenal cortex carcinoma.