CEP55 (Centrosome protein 55) was considered essential for cell cycle processes, and there were increasing evidences that up-regulation of CEP55 was involved in the development and progression of various malignancies, including liver cancer [16], bladder cancer [17], anaplastic thyroid cancer [18], non-small-cell lung cancer [19, 20] and colorectal cancer [21]. Here, CEP55 is linked to thyroid gland undifferentiated (anaplastic) carcinoma.