Expression levels of BNIP3, EEF2, FOXO1, HSPA5, KLHL24, MAP1LC3B, PEA15, PTEN, RAB11A, RB1CC1, RPS6KB1, SAR1A, ST13, and VAMP3 genes were significantly lower in PAD patients as compared to non-PAD controls (Fig. 2C). The gene discussed is RPS6KB1; the disease is peripheral arterial disease.