ERBB2 and invasive ductal breast carcinoma: TCGA-A8-A08S is a triple-positive (for ER, PR and HER2) invasive ductal carcinoma from a 71-year-old woman (Fig. 2c, top), and its genome showed multiple focally amplified segments in 11q and 17q, encompassing CCND1 and ERBB2, respectively.