CXCL8 and cancer: Inflammatory stimulants (e.g., CXCL1, CXCL2 and CXCL8) can stimulate neutrophil chemotaxis and activation to generate chromatin webs, thereby inducing NET formation in the omentum, a preferential metastasis site of ovarian cancer, while inhibition of NETs decreased the implantation of cancer cells [281].