CCR7 and neoplasm: A recent study was possibly inspired by the role of lncRNAs in the epigenetic regulation of chemokine signals; for example, breast cancer antigen-resistance 4 (BCAR4) mediates cooperative epigenetic regulation of the CCR7-CCL21 axis to promote tumor cell migration [239] and regulates DC differentiation by interacting with transcription factors [260]; the study identified epigenetic regulation of the timely termination of DC trafficking at the late stage to prevent unwanted inflammation [261].