CCL19 and neoplasm: Despite there being no significant changes in CCL19 expressed in an analysis of TCGA data, higher CCL19 expression and secretion were found in metastatic nodes of patients with head and neck squamous cell carcinoma (HNSC) than in benign nodes or primary tumors, and the CCL19-CXCR5 axis was found to exert prosurvival signaling associated with tumor progression and disease relapse [300].