Genetic loss-of-function of CCR5/RANTES (CCR5-Δ32, a 32-bp natural deletion resulting in a nonfunctional receptor) confers HIV-1 resistance [123, 124], although CCR5-Δ32 was not shown to be a factor protecting against HIV infection in an analysis of ClinVar data (Table 5). The gene discussed is CCR5; the disease is HIV infectious disease.