CXCR3 and systemic lupus erythematosus: A detailed analysis of the bulk and single-cell transcriptomic, epigenetic, and functional profiles of lupus LDGs showed that lupus neutrophil subsets differed phenotypically and functionally in terms of NET formation, chemotaxis mediated by formyl peptide receptors 1 (FPR1), CXCR1 and CXCR3, and other processes, suggesting neutrophil heterogeneity and the putative role of neutrophils in the pathogenesis of SLE associated with vascular damage [274].