To understand the transcriptional networks operating in Utx-null myeloma cells, we performed ATAC-seq in plasma cells from young Cγ1-Cre negative control, BrafV600E and UtxΔ/Δ mice (24-27-week-old), and BU749 (UtxΔ/ΔBrafV600E) plasma cells. Here, KDM6A is linked to plasma cell myeloma.