In particular, we identified a specific signature of glycolysis-related genes in BRAF-like tumours, which display the overexpression of SLC2A1, SLC2A3, HK3, PFKFB3, PKM, LDHA and SLC16A3 (alias Mct4, the membrane channel regulating lactate efflux). The gene discussed is PFKFB3; the disease is neoplasm.