The recommendation was updated in 202239,47, in which, most mutated genes found in the study were included in the hereditary parkinsonism (DCTN1 in atypical parkinsonism or complex phenotypes; GCH1, PLA2G6, and TH in combined phenotypes; GBA, ATXN2 and MAPT in disorders that usually present with other phenotypes but can have predominant parkinsonism) except for PSEN1 and ATXN3. Our work might improve the understanding of nomenclature system and offer further clues to the system. This evidence concerns the gene PSEN1 and Parkinsonism.