Indeed, treatment of tumor cells with supernatants from sNK cells not only increased the differentiation antigens such as MHC-class I, CD54, PDL-1 but it also curtailed their growth and made the tumors susceptible to chemotherapeutic drugs in in vitro experiments published previously and shown in here (12) (Figures 3, S3, S6). The gene discussed is ICAM1; the disease is neoplasm.