IFNG and neoplasm: Increase or restoration of IFN-γ secretion and NK cell-mediated cytotoxicity by bone marrow, splenocytes and PBMCs were seen in sNK cell injected tumor-bearing mice, and both these functions were further increased with the combination of sNK cells and CDDP treatment of tumor implanted mice when compared to those with tumor alone implanted mice (Figures 4F, G, S4, S5).