CYP21A2, as well as MSH5, PPP1R18, and NEU1 have been demonstrated by previous GWASs associated with other autoimmune disorders such as RA, ankylosing spondylitis (AS), T1DM, and SLE (31–33, 43, 44). The gene discussed is CYP21A2; the disease is systemic lupus erythematosus.