(19) reported that knockdown of NCOA5 in breast cancer cells significantly decreased the expression levels of N-cadherin and Vimentin, whereas increased the expression levels of E-cadherin, on the contrary, upregulation of N-cadherin and Vimentin expression or downregulation of E-cadherin expression contribute to epithelial-mesenchymal transition (20). This evidence concerns the gene CDH1 and breast carcinoma.