Study of the association between CD66b expression within the CD45+CD68 compartment and ICI resistance, which however, not observed in ICI-untreated lung cancer patients (28); characterization of 4 molecularly unique compartments: tumor, leukocyte, macrophage, and immune stroma where different biomarkers in specific compartments show improved survivals in heck and neck SCC (29). Here, CEACAM8 is linked to lung carcinoma.