Tumor size ≥5 cm (P < 0.001), AFP ≥20 ng/L (P < 0.001), ALT ≥40 U/L (P = 0.006), cirrhosis (P = 0.002), and tumor RECIST response (P = 0.008) were independent risk factors of PFS (Table 4). This evidence concerns the gene GPT and neoplasm.