COL10A1 and subepithelial mucinous corneal dystrophy: Loss‐of‐function mutations of COL10A1 gene were reported in a hereditary skeletal disease, Schmid‐type metaphyseal chondrodysplasia (SMCD),(12) which is characterized by moderate short limbs and short stature and a waddling gait caused by bowed legs.(13) A large number of different mutations have been reported, and almost all of them were found in NC1 domain.(14) Half of cases were caused by missense mutations producing mutant α1(X), which interferes with normal α1(X) to form a triple helix.