NR3C1 and type 2 diabetes mellitus: For example, alterations in circulating molecular features have been implicated in mitochondrial dysfunction and inflammation,2,3,4,5,6,7,8 delayed wound healing,9,10,11 cardiovascular diseases,12,13,14,15 metabolic disorders,2,7,16,17 type 2 diabetes mellitus (T2DM),18 chronic pain,19,20 oxidative stress associated with inflammation and endothelial cell dysfunction,21 immune modulation,22,23 glucocorticoid receptor sensitivity,3 epigenetic aging,24 neurotrophic activity,25 and disease progression,26 including biomarker panels to facilitate screening for PTSD diagnosis.8