C3 and Cognitive impairment: Potential genetic risk factors were found to be related with proteins significantly associated with wound healing and inflammatory response (PIK3CG and GRB2), neurogenesis (CAMK1D and NCAM1), cognitive disorders (KIRREL3, CADM1, ROBO2, and C3), vasculature development/angiogenesis (HS6ST1 and EFNA5), oxidative stress, and regulation of nitric oxide (MB).