To determine whether the increased OGDHL gene body methylation may be associated with more aggressive disease, matched primary prostate tumours and bone metastases (pairs from the same patients), previously profiled by Wilkinson et al. [7] using the Illumina MethylationEPIC beadchip, were interrogated for the two OGDHL probes cg08846770 and cg00898123 identified in our analysis. Here, OGDHL is linked to prostate neoplasm.