ELOVL1 and Alzheimer disease: AD progression was also associated with changes in enzymatic activities involved in fatty acid biosynthesis specifically compromising elovl1-3-7b (Spearman’s Rho=0.590, correlation p-value=0.001), elovl1-3-7c (Spearman’s Rho= -0.584, correlation p-value=0.002), and peroxisomal β-oxidation (Spearman’s Rho=0.402, correlation p-value=0.045) (Table 4).