Moreover, increasing sialic acidification or α-1,3 fucosylation mediated by FUT4/FUT6 of EGFR in lung cancer cells inhibits its dimerization and phosphorylation, and reducing core fucosylation mediated by FUT8 induces the same effects and inhibits the activation of various receptors and downstream pathways [76]. Here, EGFR is linked to lung carcinoma.