Even though ARHGAP15 loci showed non-significant p-values of 0.24–0.99 in the AA GWAS, the effect directions of ARHGAP15 loci were mostly positive and substantial, ranging from 1.111 to 1.464 in AA diverticulitis GWAS, except few loci which showed negative ORs (S3 Table). Here, ARHGAP15 is linked to Colonic diverticula.