ARHGAP15 and diverticular disease: For example, rs6734367, the strongest ARHGAP15 locus reported in Maguire et al. [17] showed positive OR of 1.010 in the original study, whereas it presents an OR as high as 1.177 (diverticulosis) and 1.280 (diverticulitis) in our EA GWAS with the same allelic direction (S6 Table).