FAS and hereditary gingival fibromatosis: Hereditary gingival fibromatosis (HGF) was found to be associated with four biomarkers according to two previous studies.34,35 According to Almeida et al.34 (2005), the production of Fatty Acid Synthase (FAS) activity was greater in patients with HGF than in others, and inhibition of FAS caused a significant reduction in the production of fibroblasts, even in healthy patients.