While the concentrations of sLRP1 and Caspase 3 were significantly lower in the AD group (2.70 ± 0.70 μg/ml, and 6.53 ± 4.79 ng/ml, P < 0.05), when compared with these in the CN group (3.59 ± 0.92 μg/ml, and 9.83 ± 6.31 ng/ml). Here, CASP3 is linked to Alzheimer disease.