Additionally, miR-424-5p was also suggested to mediate the function of circRNAs and lncRNAs in human cancers, such as the promoter role of circRNA ACTN4 in cholangiocarcinoma and the promoted effect of lncRNA MYLK-AS1 in hepatocellular carcinoma [24, 25]. The gene discussed is ACTN4; the disease is cholangiocarcinoma.