In the Kaplan–Meier plotter database, higher FDX1 expression was associated with poorer OS and relapse-free survival (RFS) in HNSC (head and neck squamous cell carcinoma) (n = 499, OS: HR = 1.47, P = 0.0053; n = 124, RFS: HR = 2.41, P = 0.018; Fig. 3F,G) and PDAC (pancreatic ductal adenocarcinoma) (n = 177, OS: HR = 1.57, P = 0.031; n = 69,RFS: HR = 2.79, P = 0.015; Fig. 3H,I). Here, FDX1 is linked to pancreatic ductal adenocarcinoma.