In BRCA, GBMLGG (glioma), HNSC, LGG, OSCC (oral squamous cell carcinoma), PAAD (pancreatic adenocarcinoma), PCPG, PRAD, READ, SARC, SKCM, TGCT (testicular germ cell tumors), UCEC and UVM (uveal Melanoma), There was a positive relationship between FDX1 expression and immune checkpoint genes especially in OSCC, where 37 of 47 immune checkpoint genes displayed a relationship with FDX1. This evidence concerns the gene FDX1 and oral cavity squamous cell carcinoma.