To further determine whether PRMT1-mediated change in PD-L1 expression is cGAS-dependent, we depleted endogenous cGAS in CT26, MC38, and 4T1 mouse tumor cells, and found a significant reduction in mPD-L1 expression in these cells (Fig. 6c, Supplementary Fig. 6h–j). This evidence concerns the gene CD274 and neoplasm.