DDX53 and cancer: To demonstrate the inhibitory effect of PRMT1 in cancer immune surveillance through methylation of cGAS in vivo, we measured immune cell infiltration in a syngeneic mouse model of engraftment with either CT26-cGAS-WT or CT26-cGAS-KO cells after treatment with PRMT1 inhibitor MS023 (Fig. 5j, Supplementary Fig. 5v).