When we divided the patients into two groups based on the occurrence of CVD events, we observed several differences in variables, such as age, sex, diabetes, hypertension, smoking, total cholesterol, HDL cholesterol, baseline LDL cholesterol, the LDL cholesterol year score, the prevalence of FH pathogenic variants, and the CAC score between the groups (see Supplementary material online, Table S1). Here, FH is linked to diabetes mellitus.