NUPR1 and infection: On the other hand, both bacteria inhibited the upstream regulators CDKN1A, DUSP1, KDM5B, MAVS, MRTFB, NR3C1, NUPR1, TAZ, TEAD1 and TEAD2. Six hours of infection with the H. pylori wt strain activated upstream regulators ATF6 and CIP2A while TEAD3 and TEAD4 were inhibited.