However, the enriched GO terms representing “Cell death” or “Apoptotic process” (GO:0010941, GO:0008219, GO:0043067 and GO:0012501) were distinctly present after the extended infection with the ΔhtrA mutant, suggesting that H. pylori HtrA may be implicated in the inhibition of host cell apoptotic pathways. The gene discussed is HTRA1; the disease is infection.