IDH1 and glioblastoma: Tumor PGBM underwent extensive histopathological and genomic analysis for clinical purposes and demonstrated diffuse and high-grade glioblastoma histology, IDH1 mutation (IDH1 c.395G>A [p.Arg132His]), MGMT promoter methylation profile, TERT promoter wild-type, and absence of 1p/19q codeletion.