In contrast, in CALB1-expressing tumors, transcription of the same mediators was minimal in cancer cells and instead was found in myeloid cells (CXCL2, CXCL8) and/or tumor-associated fibroblasts (CXCL5, CXCL6) (Figure 6C and Supplemental Figure 16). This evidence concerns the gene CXCL2 and cancer.