CD4 and food allergy: To better understand how food-induced gut CD4+ T cells contribute to tolerance and how these responses are perturbed in the context of food allergy, we combined a naïve T cell fate-mapping mouse model (iSellTomato; Merkenschlager et al., 2021) with a cholera toxin (CT) mouse model of food allergy (Jimenez-Saiz et al., 2017).