LEF1 and lung carcinoma: By the establishment of a miRNA-transcription factor (TF)-target gene network, Jiao et al found that MiR-34a-5p/ miR-34c-5p/miR-302b-3p—lymphoid enhancer binding factor 1 (LEF1)—cyclin-D1 (CCND1)/Wnt family member 1 (WNT1)/v-myc avian myelocytomatosis viral oncogene homolog (MYC) axis played a role in curcumin-mediated inhibition of lung carcinoma cell metastasis [29].