In addition, two baselines from the Atherosclerosis Risk in Communities (ARIC) Study, including 9967 participants aged 54 to 74 years, showed that lower estimated glomerular filtration rate (eGFR) based on cystatin C or β2-microglobulin, but not creatinine was associated with dementia [45]. The gene discussed is HLA-G; the disease is dementia.