When general stress factors are eliminated, blood glucose level can be restored to baseline; (3) lack of insulin antagonism in high glucose water during intravenous fluid replacement for inpatients with iatrogenic acute cerebral apoplexy; (4) placeholder effect: the probability of post-stroke hyperglycemia is significantly higher in patients with stroke near the midline than in those far from the midline, with a decreasing incidence from the brainstem > thalamus > basal ganglia > lobe. This evidence concerns the gene INS and stroke disorder.