The cut-off value of serum BNP level in predicting the clinical outcome of all patients was 195.51 pg/mL, with a sensitivity of 79.52% and a specificity of 68.69%, and that of CE stroke patients was 470.58 pg/mL, with a sensitivity of 62.50% and a specificity of 79.31%. This evidence concerns the gene NPPB and Stroke.