In this study, we used two-sample MR based on GWAS summary statistics of mTORC1-associated proteins in the European population to investigate the causal association of mTORC1-associated proteins (RPS6K, EIF4EBP, EIF-4E, EIF-4G, and EIF4A) with PD. The gene discussed is EIF4G1; the disease is Parkinson disease.