In breast cancer [69], researchers have found that this preparation occurs via the deployment of vesicles that will promote the production of growth factors and ECM proteins to create a welcoming environment for the establishment of a new tumor, namely, fibronectin to promote tumor cell engraftment, growth, and the recruitment of MMPs to degrade the basement membrane [60], which is in line with our results. This evidence concerns the gene FN1 and neoplasm.