EGFR and non-small cell lung carcinoma: While there exist multiple treatment options for treating NSCLC-BM, including whole-brain radiotherapy (WBRT), stereotactic radiosurgery (SRS), and, more rarely, surgical resection, the standard of care has shifted to the use of EGFR-directed tyrosine kinase inhibitors (EGFR-TKIs) [8,9,10].