PTGS2 and colorectal cancer: Specific functions of genes in the model are consistent with amplified epithelial–mesenchymal transition, mitogenesis, mutagenesis, angiogenesis, cell survival/dysregulated apoptosis, and metastasis in response to the overexpression of COX1, COX2, ALOX5 and ALOX5AP in the inflammogenesis of colorectal cancer.