AKT1 and Miyoshi myopathy: MM.1S, a cell line with detectable p-AKT and representing MM with a poor prognosis, was the only MM cell line sensitive to the AKT inhibitor capivasertib [37] (IC50 = 0.058 μM), and some of the screened PI3K inhibitors, such as the pan-class I PI3K inhibitor pictilisib [38] (IC50 = 0.51 μM) (Figure 1C and Figure S1A,B).