Treatment with the combination of N1, FSL-1, R848, and anti-CTLA4 or the combination of N1, FSL-1, anti-CTLA4, and SX882 induced 4T1 tumor regressions with 20% of treated 4T1 tumor-bearing mice achieving a complete response and remaining in remission (Figure 2B–D). Here, CTLA4 is linked to neoplasm.