However, as the disease progresses, activated keratinocytes play a central role in fostering tumor cell growth and survival via recruiting Th2-type cells in the skin through the production of Th2-type chemoattracting molecules including CCL17, CCL22, and CCL27 that lead to a dampening of the Th1-type anti-tumor immune response [36]. Here, CCL27 is linked to neoplasm.