Patients with benign conditions including psoriasis and early-stage CTCL patients show high expression of Th1-type cytokines, including IL-2 and IFN-γ, while late-stage patients without blood involvement demonstrate high expression levels of Th2-type cytokines, among which are IL-5, IL-10, IL-13, and IL-17 [40]. This evidence concerns the gene IL13 and primary cutaneous T-cell non-Hodgkin lymphoma.